Human papillomavirus is a group of more than 100 related DNA viruses that have the ability to infect the skin or mucous membranes. HPV is the most common sexually transmitted virus in the United States. HPV types 6 & 11 infect the internal or external mucosa of the anal or genital area of both men and women resulting in appearance of flat, papular or cauliflower-like growths or anogenital warts (AGWs). Approximately one to two percent of the sexually active population between the ages of 15-49 develop AGWs as the primary clinical manifestation of HPV infection.
In mature markets, more than half of the patients visiting a physician because of AGWs receive some form of treatment, typically, a combination of pharmacological and surgical measures. However, there are no satisfactory options: current treatments have substantial local side effects (pain, itching, inflammation), low clearance rates, and a high incidence of recurrence.